Tanya Scharton‐Kersten

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α

Ricardo T. Gazzinelli, Maria Wysocka, Sara Hieny et al. · The Journal of Immunology · 1996 · 926 citations · Full text

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas

Caetano Reis e Sousa, Sara Hieny, Tanya Scharton‐Kersten et al. · The Journal of Experimental Medicine · 1997 · 912 citations · Full text

Microbial Pathogens, Adaptive Immune System, Innate Immune System +24

Inducible Nitric Oxide Is Essential for Host Control of Persistent but Not Acute Infection with the Intracellular Pathogen <i>Toxoplasma gondii</i>

Tanya Scharton‐Kersten, George Yap, Jeanne Magram et al. · The Journal of Experimental Medicine · 1997 · 433 citations · Full text

Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture

Guido Franzoso, Louise Carlson, Ljiljana Poljak et al. · The Journal of Experimental Medicine · 1998 · 425 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +17

IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis.

Tanya Scharton‐Kersten, Luís Afonso, Maria Wysocka et al. · The Journal of Immunology · 1995 · 416 citations

Adaptive Immune System, Immunology, Il-12 Function +18