Sieger Leenstra

<i>IDH1</i>mutations at residue p.R132 (IDH1^R132) occur frequently in high-grade gliomas but not in other solid tumors

Fonnet E. Bleeker, Simona Lamba, Sieger Leenstra et al. · Human Mutation · 2009 · 366 citations · Full text

Engineering, Genetics, Pathology +19

Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins

Eleonora Aronica, Jan A. Gorter, Helen Ijlst‐Keizers et al. · European Journal of Neuroscience · 2003 · 302 citations

Neurobehavioral Status and Health-Related Quality of Life in Newly Diagnosed High-Grade Glioma Patients

Martin Klein, J.J. Heimans, Henk M. van der Ploeg et al. · Journal of Clinical Oncology · 2001 · 261 citations

Transcriptome analysis reveals tumor microenvironment changes in glioblastoma

Youri Hoogstrate, Kaspar Draaisma, Santoesha A. Ghisai et al. · Cancer Cell · 2023 · 231 citations · Full text

Neuro-oncology, Glioma, Tumor Heterogeneity +13

The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids

Philip C. De Witt Hamer, Angela A.G. van Tilborg, Paul P. Eijk et al. · Oncogene · 2007 · 218 citations · Full text

Developmental Biology, Human Malignant Glioma, Tumor Heterogeneity +9