Sungsoon Fang

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

Sungsoon Fang, Jae Myoung Suh, Shannon M. Reilly et al. · Nature Medicine · 2015 · 711 citations · Full text

Medicine, Pharmacology, Physiology +15

FXR Regulates Intestinal Cancer Stem Cell Proliferation

Ting Fu, Sally Coulter, Eiji Yoshihara et al. · Cell · 2019 · 464 citations · Full text

Medicine, Cell Biology, Oncology +10

FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States

Jongsook Kim Kemper, Zhen Xiao, Bhaskar Ponugoti et al. · Cell Metabolism · 2009 · 322 citations · Full text

Life Sciences, Biochemistry, Molecular Genetics +10

Depletion of fat-resident Treg cells prevents age-associated insulin resistance

Sagar P. Bapat, Jae Myoung Suh, Sungsoon Fang et al. · Nature · 2015 · 321 citations

Medicine, Endocrinology, Immunology +13

Ligand-activated Pregnane X Receptor Interferes with HNF-4 Signaling by Targeting a Common Coactivator PGC-1α

Sonali Bhalla, Sungsoon Fang, Lingjin Xiang et al. · Journal of Biological Chemistry · 2004 · 224 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17