Hisahiko Sekihara

PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance

Naoto Kubota, Yasuo Terauchi, Hiroshi Miki et al. · Molecular Cell · 1999 · 1.4K citations · Full text

Insulin Resistance, Obesity, Metabolic Syndrome +10

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1

Hiroyuki Tamemoto, Takashi Kadowaki, Kazuyuki Tobe et al. · Nature · 1994 · 1.1K citations

Insulin Resistance, Metabolic Syndrome, Insulin Signaling +11

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

Naoto Kubota, Kazuyuki Tobe, Yasuo Terauchi et al. · Diabetes · 2000 · 524 citations · Full text

Insulin Receptor, Insulin Signaling, Causes Type 2 +20

Peroxisome proliferator-activated receptor γ ligands suppress colon carcinogenesis induced by azoxymethane in mice

Emi Osawa, Atsushi Nakajima, Koichiro Wada et al. · Gastroenterology · 2003 · 192 citations

Suppress Colon Carcinogenesis, Oncology, Medicine +6

Treatment of hepatocellular carcinoma with radiofrequency ablation: Radiologic-histologic correlation during follow-up periods

Manabu Morimoto, Kazuya Sugimori, Kazuhito Shirato et al. · Hepatology · 2002 · 155 citations · Full text

Surgical Oncology, Pathology, Interventional Radiology +18