Hisahiko Sekihara

PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance

Naoto Kubota, Yasuo Terauchi, Hiroshi Miki et al. · Molecular Cell · 1999 · 1.4K citations · Full text

Life Sciences, Biochemistry, Physiology +12

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1

Hiroyuki Tamemoto, Takashi Kadowaki, Kazuyuki Tobe et al. · Nature · 1994 · 1.1K citations

Medicine, Biochemistry, Endocrinology +16

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

Naoto Kubota, Kazuyuki Tobe, Yasuo Terauchi et al. · Diabetes · 2000 · 527 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Peroxisome proliferator-activated receptor γ ligands suppress colon carcinogenesis induced by azoxymethane in mice

Emi Osawa, Atsushi Nakajima, Koichiro Wada et al. · Gastroenterology · 2003 · 193 citations

Medicine, Oncology, Pharmacology +12

Treatment of hepatocellular carcinoma with radiofrequency ablation: Radiologic-histologic correlation during follow-up periods

Manabu Morimoto, Kazuya Sugimori, Kazuhito Shirato et al. · Hepatology · 2002 · 156 citations · Full text

Medicine, Oncology, Radiology +17