Ulrich Steidl

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

Eric M. Pietras, Cristina Mirantes-Barbeito, Sarah Fong et al. · Nature Cell Biology · 2016 · 677 citations

Inflammation, Developmental Biology, Bone Marrow Failure +13

MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

Christian Steidl, Sohrab P. Shah, Bruce W. Woolcock et al. · Nature · 2011 · 603 citations

Lymphoid Neoplasia, Lymphoid Cancers, Medicine +5

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Luis A. Carvajal, Daniela Ben Neriah, Adrien Senecal et al. · Science Translational Medicine · 2018 · 243 citations · Full text

Chemoprevention Strategy, Mixed-phenotype Acute Leukemia, Therapeutic Strategy +23

U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies

Molly A. Smith, Gaurav S. Choudhary, Andrea Pellagatti et al. · Nature Cell Biology · 2019 · 243 citations

Hematological Malignancy, Innate Immune Pathways, Medicine +8

Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia

Alan H. Shih, Yanwen Jiang, Cem Meydan et al. · Cancer Cell · 2015 · 242 citations · Full text

Chromatin, Combinatorial Epigenetic Gain, Chromatin Remodeling +11