Shinya Hisakawa

Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship

Toshiaki Aoki, Hidenori Yoshizawa, Kenji Yamawaki et al. · European Journal of Medicinal Chemistry · 2018 · 156 citations

Structure Activity Relationship, Antimicrobial Susceptibility, Health Sciences +12

Highly Potent and Selective Histone Deacetylase 6 Inhibitors Designed Based on a Small-Molecular Substrate

Takayoshi Suzuki, Akiyasu Kouketsu, Yukihiro Itoh et al. · Journal of Medicinal Chemistry · 2006 · 104 citations · Full text

Design, synthesis, and biological activity of folate receptor-targeted prodrugs of thiolate histone deacetylase inhibitors

Takayoshi Suzuki, Shinya Hisakawa, Yukihiro Itoh et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 52 citations · Full text

Biological Activity, Drug Target, Biochemistry +10

Design and synthesis of non-hydroxamate histone deacetylase inhibitors: identification of a selective histone acetylating agent

Takayoshi Suzuki, Azusa Matsuura, Akiyasu Kouketsu et al. · Bioorganic & Medicinal Chemistry · 2005 · 26 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +9

Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor

Takayoshi Suzuki, Shinya Hisakawa, Yukihiro Itoh et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 18 citations · Full text

Medicinal Chemistry, Biochemistry, Prodrug Formation +9