Concepedia

Design, synthesis, and biological activity of folate receptor-targeted prodrugs of thiolate histone deacetylase inhibitors

Takayoshi Suzuki, Shinya Hisakawa, Yukihiro Itoh, Nobuaki Suzuki, Katsumasa Takahashi, Masatoshi Kawahata, Kentaro Yamaguchi, Hidehiko Nakagawa, Naoki Miyata

Bioorganic & Medicinal Chemistry Letters · 2007 · 52 citations · 18 references

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18

Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.

Steven Weitman, Richard H. Lark, Leslie R. Coney et al. · PubMed · 1992 · 1K citations

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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

Victoria M. Richon, Stéphane Emiliani, Eric Verdin et al. · Proceedings of the National Academy of Sciences · 1998 · 914 citations · Full text

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Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer

William Kevin Kelly, Owen A. O’Connor, Lee M. Krug et al. · Journal of Clinical Oncology · 2005 · 907 citations · Full text

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Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

John F. Ross, P. K. Chaudhuri, Manohar Ratnam · Cancer · 1994 · 889 citations

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A synthetic inhibitor of histone deacetylase, MS-27-275, with marked <i>in vivo</i> antitumor activity against human tumors

Akiko Saito, Takashi Yamashita, Yukiyasu Mariko et al. · Proceedings of the National Academy of Sciences · 1999 · 696 citations · Full text

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