Azepanone-Based Inhibitors of Human and Rat Cathepsin K

Robert W. Marquis, Yu Ru, Steven M. LoCastro, +36

Journal of Medicinal Chemistry

Transport of l-Valine-Acyclovir Via the Oligopeptide Transporter In The Human Intestinal Cell Line, Caco-2

Remco L.A. de Vrueh, Philip L. Smith, Chao‐Pin Lee

Journal of Pharmacology and Experimental Therapeutics

Potent, Selective, Orally Active 3-Oxo-1,4-benzodiazepine GPIIb/IIIa Integrin Antagonists

James M. Samanen, Fadia E. Ali, Linda S. Barton, +30

Journal of Medicinal Chemistry

Altmetric Attention ScorePharmacotherapyExperimental PharmacologyPharmacodynamic ModelingTranslational Pharmacology +15

Structural Requirements for Interaction with the Oligopeptide Transporter in Caco-2 Cells

Ismael J. Hidalgo, Pradip K. Bhatnagar, Chao‐Pin Lee, +3

Pharmaceutical Research

Synthesis of analogs of l-valacyclovir and determination of their substrate activity for the oligopeptide transporter in Caco-2 cells

Gerda Marie Friedrichsen, Weiqing Chen, Mikael Begtrup, +3

European Journal of Pharmaceutical Sciences

Medicinal ChemistryCaco-2 CellsPharmaceutical ScienceBiochemistryOligopeptide Transporter +6

Selection of development candidates based on in vitro permeability measurements

Chao‐Pin Lee, Remco L.A. de Vrueh, Philip L. Smith

Advanced Drug Delivery Reviews

Tissue EngineeringDevelopmental BiologyEngineeringBioengineering ModelMedicine +8

Metabolism, uptake, and transepithelial transport of the diastereomers of Val-Val in the human intestinal cell line, Caco-2.

Kiyoshi Tamura, Pradip K. Bhatnagar, Joanne S. Takata, +3

Pharmaceutical Research

Molecular PhysiologyBiochemistryMedicineNatural SciencesPhysiology +6

Exploitation of the Intestinal Oligopeptide Transporter to Enhance Drug Absorption

Philip L. Smith, Evangeline P. Eddy, Chao‐Pin Lee, +1

Drug Delivery

Molecular PharmacologyGastrointestinal Peptide HormoneBiochemistryOligopeptide TransporterGastrointestinal Pharmacology +13

Endothelin-Converting Enzyme: Substrate Specificity and Inhibition by Novel Analogs of Phosphoramidon

Paul M. Keller, Chao‐Pin Lee, Ashley Fenwick, +3

Biochemical and Biophysical Research Communications

BiochemistryEndothelin-converting EnzymeMedicineSubstrate SpecificityNatural Sciences +5

Effect of Charge on Oligopeptide Transporter-Mediated Permeation of Cyclic Dipeptides Across Caco-2 Cell Monolayers

Kiyoshi Tamura, Chao‐Pin Lee, Philip L. Smith, +1

Pharmaceutical Research