Colin Osborne - Concepedia

Author

Colin Osborne

Novartis (United States)ORCID

Also Known As

C S Osborne, C. Osborne, C. S OSBORNE, C. S. Osborne, C.S. Osborne, Colin Osborne, Colin S. Osborne, Osborne, Colin

Publications

1.2K

Citations

H-Index

Concepts

All Affiliations

Novartis (United States)Novartis (Switzerland)Novartis Institutes for BioMedical Research University of Strathclyde Novartis (Austria)

About

Colin Osborne is an author at Novartis (United States) specializing in medicine, pharmacology, and drug resistance.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	718
2	Health Sciences	3	3	163
3	Natural Sciences	3	3	209
4	Engineering	2	2	129
5	Allergy	1	1	146

Colin Osborne

Publications

1.1K

Citations

H-Index

Page 1

	Year	Citations
Amino Acid Substitution in<i>Trichophyton rubrum</i>Squalene Epoxidase Associated with Resistance to Terbinafine Colin Osborne, Ingrid Leitner, Bertrand Favre, Antimicrobial Agents and Chemotherapy Terbinafine ResistanceGeneticsMolecular BiologyAmino Acid SubstitutionMolecular Genetics	2005	146
Discovery of LFF571: An Investigational Agent for <i>Clostridium difficile</i> Infection Matthew J. LaMarche, Jennifer A. Leeds, Adam Amaral, Journal of Medicinal Chemistry Bioorganic ChemistryBacteriophageInvestigational AgentBacterial PathogensPharmaceutical Chemistry	2012	116
Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV) Aurelio Bonavia, Michael Franti, Erin P. Keaney, Proceedings of the National Academy of Sciences Novel Therapeutic InterventionsMedicinal ChemistryRespiratory Syncytial VirusViral DiseaseSynthetic Virology	2011	94
Biological, Biochemical, and Molecular Characterization of a New Clinical <i>Trichophyton rubrum</i> Isolate Resistant to Terbinafine Colin Osborne, Ingrid Leitner, Bettina Hofbauer, Antimicrobial Agents and Chemotherapy	2006	88
NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models Stephanie Moquin, Oliver Simon, Ratna Karuna, Science Translational Medicine Pan-serotype InhibitorDengue VirusImmunologyAntiviral DrugNovartis Compound Library	2021	81
Investigation into the tensile properties of collagen/chondroitin-6-sulphate gels: the effect of crosslinking agents and diamines Colin Osborne, J.C. Barbenel, David W. Smith, Medical & Biological Engineering & Computing Materials ScienceBiopolymer GelEngineeringMechanical PropertiesBiomechanics	1998	69
Investigation into the biological stability of collagen/chondroitin-6-sulphate gels and their contraction by fibroblasts and keratinocytes: the effect of crosslinking agents and diamines Colin Osborne, William H. Reid, M.H. Grant Biomaterials Tissue EngineeringMechanobiologyBiocompatible MaterialEngineeringHuman Tissue	1999	60
Design, Synthesis, and Properties of a Potent Inhibitor of<i>Pseudomonas aeruginosa</i>Deacetylase LpxC Grazia Piizzi, David T. Parker, Yunshan Peng, Journal of Medicinal Chemistry	2017	45
Antifungal drug response in an<i>in vitro</i>model of dermatophyte nail infection Colin Osborne, Ingrid Leitner, Bertrand Favre, Medical Mycology Antifungal AgentAntibioticsFungal PathogenAntifungal AgentsInvasive Mycelial Growth	2004	42
Antibacterial Optimization of 4-Aminothiazolyl Analogues of the Natural Product GE2270 A: Identification of the Cycloalkylcarboxylic Acids Matthew J. LaMarche, Jennifer A. Leeds, Kerri Amaral, Journal of Medicinal Chemistry	2011	41

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