Jan Piet van Hamburg

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin‐17A production

Jan Piet van Hamburg, Patrick S. Asmawidjaja, Nadine Davelaar et al. · Arthritis & Rheumatism · 2010 · 328 citations

Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate

Takeshi Isoda, Amanda J. Moore, Zhaoren He et al. · Cell · 2017 · 327 citations · Full text

Chromatin, Transcriptional Regulation, Chromatin Remodeling +12

GATA-2 Plays Two Functionally Distinct Roles during the Ontogeny of Hematopoietic Stem Cells

Kam‐Wing Ling, Katrin Ottersbach, Jan Piet van Hamburg et al. · The Journal of Experimental Medicine · 2004 · 309 citations · Full text

Genetics, Cell Specialization, Embryology +18

1,25‐dihydroxyvitamin D₃ modulates Th17 polarization and interleukin‐22 expression by memory T cells from patients with early rheumatoid arthritis

Edgar M. Colin, Patrick S. Asmawidjaja, Jan Piet van Hamburg et al. · Arthritis & Rheumatism · 2009 · 263 citations · Full text

Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice

Laurens P. Kil, Marjolein J. W. de Bruijn, Menno van Nimwegen et al. · Blood · 2012 · 197 citations · Full text