Jack R. Kirsch

Biofunctionalization of 3D-printed silicone implants with immunomodulatory hydrogels for controlling the innate immune response: An in vivo model of tracheal defect repair

Julien Barthès, Prescillia Lagarrigue, Vladimir Riabov et al. · Biomaterials · 2020 · 71 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +17

Complete substitution with modified nucleotides in self-amplifying RNA suppresses the interferon response and increases potency

Joshua E. McGee, Jack R. Kirsch, Devin Kenney et al. · Nature Biotechnology · 2024 · 63 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Establishing health state valuations for disease specific states: an example from heart disease

Jack R. Kirsch, Alistair McGuire · Health Economics · 2000 · 56 citations

Pharmacy, Cardiology, Pharmacoeconomics +17

Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity

Regina Salvat, Deeptak Verma, Andrew S. Parker et al. · Proceedings of the National Academy of Sciences · 2017 · 39 citations · Full text

Pharmacy, Biotechnology, Immunology +17

Radiolabeled Biodistribution of Expansile Nanoparticles: Intraperitoneal Administration Results in Tumor Specific Accumulation

Aaron H. Colby, Jack R. Kirsch, Amit Patwa et al. · ACS Nano · 2023 · 36 citations · Full text

Pharmacy, Oncology, Pharmacology +17