Karel Otero

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

Marina Cella, Anja Fuchs, William Vermi et al. · Nature · 2008 · 1.2K citations · Full text

Inflammation, Autoimmune Disease, Mucosal Immunology +11

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

Fabia Filipello, Raffaella Morini, Irene Corradini et al. · Immunity · 2018 · 693 citations · Full text

Inflammation, Medicine, Synaptic Transmission +11

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity

Marina Cella, Karel Otero, Marco Colonna · Proceedings of the National Academy of Sciences · 2010 · 341 citations · Full text

Il-22 Production, T-regulatory Cell, Immunology +17

Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin

Karel Otero, Isaiah R. Turnbull, Pietro Luigi Poliani et al. · Nature Immunology · 2009 · 308 citations · Full text

Inflammation, Cytokine, Signal Transduction +9

TREM2 regulates microglial cell activation in response to demyelination in vivo

Claudia Cantoni, Bryan Bollman, Danilo Licastro et al. · Acta Neuropathologica · 2015 · 299 citations · Full text

Inflammation, Neurodegenerative Diseases, Medicine +7