Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau).

Ritsuko Takada, Y. Nakatani, Alexander Hoffmann, +4

Proceedings of the National Academy of Sciences

GeneticsImmunologyTata Box-binding ProteinProtein ExpressionTfiid Tau +16

Acetoacetyl-CoA synthetase, a ketone body-utilizing enzyme, is controlled by SREBP-2 and affects serum cholesterol levels

Shinya Hasegawa, Kazuki Noda, Akina Maeda, +3

Molecular Genetics and Metabolism

OxysterolBiochemistryMedicineLiver PhysiologyCholesterol Levels +7

Prospective cohort study for identification of underlying genetic causes in neonatal encephalopathy using whole-exome sequencing

Theodora U. J. Bruun, Caro-Lyne DesRoches, Diane Wilson, +7

Genetics in Medicine

Genetic DisorderWhole-exome SequencingGeneticsGenetic EpidemiologyPediatrics +6

Acetoacetyl-CoA synthetase gene is abundant in rat adipose, and related with fatty acid synthesis in mature adipocytes

Masahiro Yamasaki, Shinya Hasegawa, Hiroaki Suzuki, +3

Biochemical and Biophysical Research Communications

ObesityBiochemistryAdipose TissuePhysiologyMetabolic Regulation +7

The Role of Acetoacetyl-CoA Synthetase, a Ketone Body-Utilizing Enzyme, in 3T3-L1 Adipocyte Differentiation

Shinya Hasegawa, Yotaro Ikeda, Masahiro Yamasaki, +1

Biological and Pharmaceutical Bulletin

Metabolic RemodelingCellular PhysiologyInsulin SignalingBiosynthesis3T3-l1 Adipocyte Differentiation +18

Acetoacetyl-CoA synthetase is essential for normal neuronal development

Shinya Hasegawa, Hiroki Kume, Sayuri Iinuma, +3

Biochemical and Biophysical Research Communications

Developmental BiologyMolecular NeuroscienceBrain DevelopmentNeurophysiologyNeurogenesis +7

High-fat diet-induced obesity stimulates ketone body utilization in osteoclasts of the mouse bone

Masahiro Yamasaki, Shinya Hasegawa, Masahiko Imai, +2

Biochemical and Biophysical Research Communications

NutritionOsteoporosisOrthopaedic SurgeryObesityMetabolic Syndrome +18

Placental extracts induce the expression of antioxidant enzyme genes and suppress melanogenesis in B16 melanoma cells

Masahiro Yamasaki, Shinya Hasegawa, Hiroshi Takahashi, +6

Natural Product Research

Porcine PeAntioxidant Enzyme GenesLipid PeroxidationCell DeathDermatology +14

Stimulation of Peritoneal Mesothelial Cells to Secrete Matrix Metalloproteinase-9 (MMP-9) by TNF-α: A Role in the Invasion of Gastric Carcinoma Cells

Teruaki Oku, Kentaro Shimada, Hiroki Kenmotsu, +6

International Journal of Molecular Sciences

ImmunologyImmunoeditingPathologyCancer BiologyGastric Carcinoma Cells +22

Transcriptional regulation of ketone body-utilizing enzyme, acetoacetyl-CoA synthetase, by C/EBPα during adipocyte differentiation

Shinya Hasegawa, Masahiro Yamasaki, Tasuku Inage, +2

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Transcriptional RegulationBiochemistryNatural SciencesAdipocyte DifferentiationPhysiology +8