Efficient evolution of human antibodies from general protein language models

Brian Hie, Varun R. Shanker, Duo Xu, +6

Nature Biotechnology

Engineering a Rugged Nanoscaffold To Enhance Plug-and-Display Vaccination

Theodora U. J. Bruun, Anne‐Marie Andersson, Simon J. Draper, +1

ACS Nano

Unsupervised evolution of protein and antibody complexes with a structure-informed language model

Varun R. Shanker, Theodora U. J. Bruun, Brian Hie, +1

Science

EngineeringStructural BioinformaticsImmunologyMolecular BiologyStructure-informed Language Model +17

A New Multicomponent Multicatalyst Reaction (MC)²R: Chemoselective Cycloaddition and Latent Catalyst Activation for the Synthesis of Fully Substituted 1,2,3-Triazoles

Kosuke Yamamoto, Theodora U. J. Bruun, Jung Yun Kim, +2

Organic Letters

Latent Catalyst ActivationFully Substituted 1,2,3-TriazolesChemical EngineeringEngineeringCross-coupling Reaction +11

Cu/Pd-Catalyzed Synthesis of Fully Decorated Polycyclic Triazoles: Introducing C–H Functionalization to Multicomponent Multicatalytic Reactions ((MC)²R)

Zafar Qureshi, Jung Yun Kim, Theodora U. J. Bruun, +2

ACS Catalysis

EngineeringInternal AlkynesOrganic ChemistryChemistryHeterocycle Chemistry +14

Phenotypic and genotypic spectrum of congenital disorders of glycosylation type I and type II

Amal Al Teneiji, Theodora U. J. Bruun, Sarah Sidky, +8

Molecular Genetics and Metabolism

GlycoproteomicsDevelopmental AnomalyMendelian DisorderGenetic DisorderMedicine +8

Phenotype, biochemical features, genotype and treatment outcome of pyridoxine-dependent epilepsy

Amal Al Teneiji, Theodora U. J. Bruun, Dawn Cordeiro, +5

Metabolic Brain Disease

MedicineNeuropharmacologyNeuroscienceNeurologyPharmacology +2

Prospective cohort study for identification of underlying genetic causes in neonatal encephalopathy using whole-exome sequencing

Theodora U. J. Bruun, Caro-Lyne DesRoches, Diane Wilson, +7

Genetics in Medicine

Genetic DisorderWhole-exome SequencingGeneticsGenetic EpidemiologyPediatrics +6

Treatment outcome of creatine transporter deficiency: international retrospective cohort study

Theodora U. J. Bruun, Sarah Sidky, Anabela Bandeira, +12

Metabolic Brain Disease

UrologyCreatine Transporter DeficiencyRenal FunctionKidney FailureInherited Metabolic Disease +4

Broad and Durable Humoral Responses Following Single Hydrogel Immunization of SARS‐CoV‐2 Subunit Vaccine

Ben S. Ou, Olivia M. Saouaf, Jerry Yan, +5

Advanced Healthcare Materials

EngineeringSars‐cov‐2 Subunit VaccineImmunologyBiomedical EngineeringImmunotherapy +16