Varun R. Shanker

Efficient evolution of human antibodies from general protein language models

Brian Hie, Varun R. Shanker, Duo Xu et al. · Nature Biotechnology · 2023 · 450 citations · Full text

Life Sciences, Evolutionary Biology, Immunology +14

Unsupervised evolution of protein and antibody complexes with a structure-informed language model

Varun R. Shanker, Theodora U. J. Bruun, Brian Hie et al. · Science · 2024 · 134 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

Efficient evolution of human antibodies from general protein language models and sequence information alone

Brian Hie, Duo Xu, Varun R. Shanker et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 29 citations · Full text

Life Sciences, Bioinformatics, Evolutionary Biology +13

Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein–Protein Interactions Using Phage Display

S P Wang, Franco F. Faucher, Matilde Bertolini et al. · Journal of the American Chemical Society · 2025 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Enhancing proteasomal processing improves survival for a peptide vaccine used to treat glioblastoma

Mario Fidanza, Puja Gupta, Anin Sayana et al. · Science Translational Medicine · 2021 · 19 citations · Full text

Medicine, Immunology, Oncology +17