Varun R. Shanker

Efficient evolution of human antibodies from general protein language models

Brian Hie, Varun R. Shanker, Duo Xu et al. · Nature Biotechnology · 2023 · 403 citations · Full text

Unsupervised evolution of protein and antibody complexes with a structure-informed language model

Varun R. Shanker, Theodora U. J. Bruun, Brian Hie et al. · Science · 2024 · 107 citations · Full text

Engineering, Structural Bioinformatics, Immunology +19

Efficient evolution of human antibodies from general protein language models and sequence information alone

Brian Hie, Duo Xu, Varun R. Shanker et al. · 2022 · 29 citations · Full text

Machine Learning, Efficient Evolution, Immunology +23

Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein–Protein Interactions Using Phage Display

S P Wang, Franco F. Faucher, Matilde Bertolini et al. · Journal of the American Chemical Society · 2025 · 20 citations

Peptide Engineering, Molecular Biology, Peptide Therapeutics +16

Enhancing proteasomal processing improves survival for a peptide vaccine used to treat glioblastoma

Mario Fidanza, Puja Gupta, Anin Sayana et al. · Science Translational Medicine · 2021 · 18 citations