William H. Brissette

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

Jeffrey H. Hanke, Joseph P. Gardner, Robert L. Dow et al. · Journal of Biological Chemistry · 1996 · 1.9K citations · Full text

Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

Paul S. Changelian, Mark E. Flanagan, Douglas J. Ball et al. · Science · 2003 · 667 citations · Full text

Immunology, Cell Death, Immunotherapy +21

Absence of the P2X7 Receptor Alters Leukocyte Function and Attenuates an Inflammatory Response

Jeffrey M. Labasi, Nina Petrushova, Carol Donovan et al. · The Journal of Immunology · 2002 · 486 citations · Full text

Collagen Degradation Products, Immune Regulation, Immunology +19

Impaired Invariant Chain Degradation and Antigen Presentation and Diminished Collagen-Induced Arthritis in Cathepsin S Null Mice

T Nakagawa, William H. Brissette, Paul D. Lira et al. · Immunity · 1999 · 411 citations · Full text

Inflammation, Rheumatology, Rheumatoid Disorder +12

Discovery of CP-690,550: A Potent and Selective Janus Kinase (JAK) Inhibitor for the Treatment of Autoimmune Diseases and Organ Transplant Rejection

Mark E. Flanagan, Todd A. Blumenkopf, William H. Brissette et al. · Journal of Medicinal Chemistry · 2010 · 331 citations · Full text

Immunology, Janus Tyrosine Kinases, Immunotherapy +19