Aigars Jirgensons - Concepedia

Author

Aigars Jirgensons

Latvijas Organiskās Sintēzes Institūts ORCID

Also Known As

A Jirgensons, A. JIRGENSONS, A. Jirgensons, Aigars Jirgensons, Aigars Jirgensons (1435216), Jirgensons, A., Jirgensons, Aigars, Narayanan, Aswini

307

Publications

1.5K

Citations

H-Index

Concepts

All Affiliations

Latvijas Organiskās Sintēzes Institūts Latvian Biomedical Research and Study Centre University of Latvia Institute of Organic Synthesis MerLion Pharma (Germany)

About

Aigars Jirgensons is an author at Latvijas Organiskās Sintēzes Institūts specializing in natural sciences, biochemistry, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	16	19	512
2	Medicine	13	18	492
3	Engineering	11	11	262
4	Health Sciences	1	1	12
5	Social Sciences	1	1	45

Aigars Jirgensons

Publications

1.2K

Citations

H-Index

Page 1

	Year	Citations
Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate Olga Bobiļeva, Raitis Bobrovs, I. Kanepe, ACS Medicinal Chemistry Letters	2021	65
Fragment-Based Discovery of 2-Aminoquinazolin-4(3<i>H</i>)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV Dace Rasiņa, Mārtiņš Otikovs, Ja̅nis Leita̅ns, Journal of Medicinal Chemistry Antiparasitic AgentMalariaChemical BiologyPharmaceutical ChemistryMolecular Pharmacology	2015	64
Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target Chrislaine Withers‐Martinez, Catherine Suárez, Simone Fulle, International Journal for Parasitology Protein AssemblyMalariaProteasomeMolecular BiologyPlasmodium Falciparum	2012	58
Plasmepsin Inhibitory Activity and Structure-Guided Optimization of a Potent Hydroxyethylamine-Based Antimalarial Hit Kristaps Jaudzems, Kaspars Tārs, Gundars Maurops, ACS Medicinal Chemistry Letters Inhibitory ActivityMedicinal ChemistryPlasmepsin Inhibitory ActivityBiochemistryAntiparasitic Agent	2014	55
A Practical Synthesis of tert-Alkylamines via the Ritter Reaction with Chloroacetonitrile Aigars Jirgensons, Valerjans Kauss, Ivars Kalvinsh, Synthesis Chemical EngineeringPractical SynthesisRitter ReactionEngineeringChloroacetyl Group	2000	55
1408777: Experimental Crystal Structure Determination Marija Skvorcova, Liene Grigorjeva, Aigars Jirgensons Crystal StructureStructure DeterminationStructure ElucidationChemistryCrystallography	2015	49
Synthesis of Hydroxamic Acids by Activation of Carboxylic Acids with<i>N</i>,<i>N</i>′-Carbonyldiimidazole: Exploring the Efficiency of the Method Natalija Usachova, Gundars Leitis, Aigars Jirgensons, Synthetic Communications Carboxylic AcidsEngineeringHydroxamic AcidsBiocatalysisHigh Purity	2010	48
Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain – relation to brain concentration Jens Nagel, Irina Belozertseva, Sergio Greco, Neuropharmacology Pain TherapyPain DisordersPain MedicineNeuropathic PainMolecular Pain	2006	45
Virtual Screening for Selective Allosteric mGluR1 Antagonists and Structure–Activity Relationship Investigations for Coumarine Derivatives Tobias Noeske, Aigars Jirgensons, Igors Starchenkovs, ChemMedChem Drug TargetCoumarine ScaffoldCoumarine DerivativesPharmacotherapyMolecular Pharmacology	2007	36
Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening Raitis Bobrovs, I. Kanepe, Nauris Narvaiss, Pharmaceuticals	2021	35

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