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A Practical Synthesis of tert-Alkylamines via the Ritter Reaction with Chloroacetonitrile
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2000
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Chemical EngineeringPractical SynthesisRitter ReactionEngineeringChloroacetyl GroupOrganic ChemistryCatalysisChemistrySynthesis MethodTertiary AlcoholsSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
Ritter reaction of tertiary alcohols with chloroacetonitrile and subsequent cleavage of chloroacetyl group in the resulting chloroacetamide with thiourea is an efficient procedure for synthesis of tert-alkylamines.