Nancy-Ellen Haynes

Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy

Joseph Grimsby, Ramakanth Sarabu, Wendy L. Corbett et al. · Science · 2003 · 537 citations

Medicine, Biochemistry, Endocrinology +17

Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Martha J. Kelly, Sherrie Pietranico-Cole, J. Douglas Larigan et al. · Journal of Medicinal Chemistry · 2014 · 215 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Metal Impurities Cause False Positives in High-Throughput Screening Campaigns

Johannes C. Hermann, Yingsi Chen, Charles Wartchow et al. · ACS Medicinal Chemistry Letters · 2012 · 122 citations

Pharmacy, Chemistry, Analytical Chemistry +14

Discovery of Piragliatin—First Glucokinase Activator Studied in Type 2 Diabetic Patients

Ramakanth Sarabu, Fred T. Bizzarro, Wendy L. Corbett et al. · Journal of Medicinal Chemistry · 2012 · 98 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery, Structure−Activity Relationships, Pharmacokinetics, and Efficacy of Glucokinase Activator (2<i>R</i>)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-<i>N</i>-thiazol-2-yl-propionamide (RO0281675)

Nancy-Ellen Haynes, Wendy L. Corbett, Fred T. Bizzarro et al. · Journal of Medicinal Chemistry · 2010 · 46 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13