Carolin Hoft

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Alison Margolskee, Adam S. Darwich, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 67 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Adam S. Darwich, Alison Margolskee, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 45 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model

Shannon Dallas, Laurent Salphati, David Gomez‐Zepeda et al. · Molecular Pharmacology · 2016 · 26 citations

Medicine, Oncology, Pharmacology +17

De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors

Ying Wang, Hongyu Zhao, J.T. Brewer et al. · Journal of Medicinal Chemistry · 2018 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Navitoclax safety, tolerability, and effect on biomarkers of senescence and neurodegeneration in aged nonhuman primates

Edward F. Greenberg, Martin J. Voorbach, Alexandra Smith et al. · Heliyon · 2024 · 23 citations · Full text

Medicine, Neurology, Pharmacology +17