James E. Orfila

Circulating heparan sulfate fragments mediate septic cognitive dysfunction

Joseph A. Hippensteel, Brian J. Anderson, James E. Orfila et al. · Journal of Clinical Investigation · 2019 · 113 citations · Full text

Neurochemical Biomarkers, Social Sciences, Heparan Sulfate Fragments +17

Autonomous CaMKII Activity as a Drug Target for Histological and Functional Neuroprotection after Resuscitation from Cardiac Arrest

Guiying Deng, James E. Orfila, Robert M. Dietz et al. · Cell Reports · 2017 · 63 citations · Full text

Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner

Hugo A. Tejeda, Luis A. Natividad, James E. Orfila et al. · Psychopharmacology · 2012 · 47 citations · Full text

Tobacco Control, Substance Abuse, Nicotine Withdrawal Syndrome +12

Delayed inhibition of tonic inhibition enhances functional recovery following experimental ischemic stroke

James E. Orfila, Himmat Grewal, Robert M. Dietz et al. · Journal of Cerebral Blood Flow & Metabolism · 2017 · 47 citations · Full text

Synaptic Transmission, Neurological Rehabilitation, Social Sciences +24

Endogenous Sex Steroids Dampen Neuroinflammation and Improve Outcome of Traumatic Brain Injury in Mice

Amy C. Clevenger, Hoon Kim, Ernesto Salcedo et al. · Journal of Molecular Neuroscience · 2018 · 47 citations · Full text

Traumatic Brain Injury, Improve Outcome, Medicine +9