Diacylglycerol Acyltransferase 1 Inhibition Lowers Serum Triglycerides in the Zucker Fatty Rat and the Hyperlipidemic Hamster

Andrew King, Jason A. Segreti, Kelly J. Larson, +6

Journal of Pharmacology and Experimental Therapeutics

Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P₅) Agonist for the Potential Treatment of Neurodegenerative Disorders

Adrian D. Hobson, Christopher M. Harris, Elizabeth L. van der Kam, +16

Journal of Medicinal Chemistry

Cell DeathExperimental PharmacologySynaptic SignalingLipid AccumulationCompound 29 +15

In vivo efficacy of acyl CoA: Diacylglycerol acyltransferase (DGAT) 1 inhibition in rodent models of postprandial hyperlipidemia

Andrew King, Jason A. Segreti, Kelly J. Larson, +8

European Journal of Pharmacology

Metabolic SyndromeAcyl CoaBiochemistryMedicinePhysiology +9

Identification and Preliminary Characterization of a Potent, Safe, and Orally Efficacious Inhibitor of Acyl-CoA:Diacylglycerol Acyltransferase 1

Vince S. C. Yeh, David W. A. Beno, Sevan Brodjian, +29

Journal of Medicinal Chemistry

Lipid AnalysisPharmacotherapyPharmaceutical ChemistryPre-clinical PharmacologyMolecular Pharmacology +17

Computer-assisted imaging algorithms facilitate histomorphometric quantification of kidney damage in rodent renal failure models

Marcin Klapczynski, Gerard D. Gagné, Sherry J. Morgan, +5

Journal of Pathology Informatics

Associations between Charlson Comorbidity Index and Surgical Risk Severity and the Surgical Outcomes in Advanced-age Patients

Kelly J. Larson, Ryan J. Hamlin, Juraj Šprung, +2

The American Surgeon

Adult Cardiac SurgeryAgingSurgical ProceduresSurgical Risk SeveritySurgery +25

Effect of the Multitargeted Receptor Tyrosine Kinase Inhibitor, ABT-869 [N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N′-(2-fluoro-5-methylphenyl)urea], on Blood Pressure in Conscious Rats and Mice: Reversal with Antihypertensive Agents and Effect on Tumor Growth Inhibition

Pamela H. Franklin, Patricia N. Banfor, Paul Tapang, +9

Journal of Pharmacology and Experimental Therapeutics

Anesthesia and organic aciduria: is the use of lactated Ringer's solution absolutely contraindicated?

Kateřina Růžková, Toby N. Weingarten, Kelly J. Larson, +3

Pediatric Anesthesia

Myoclonus in patient on fluoxetine after receiving fentanyl and low-dose methylene blue during sentinel lymph node biopsy

Kelly J. Larson, Erica D. Wittwer, Wayne T. Nicholson, +3

Journal of Clinical Anesthesia

MedicineLow-dose Methylene BluePathology