Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent

Masami Kusaka, Katsuichi Sudo, Takeshi Fujita, +4

Biochemical and Biophysical Research Communications

InflammationAntifungal AgentAngiogenesisMedicinePathology +4

Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470)

Masami Kusaka, K Sudo, Etsuya Matsutani, +5

British Journal of Cancer

AngiogenesisEndothelial Cell GrowthMedicineAngiogenesis Inhibitor Tnp-470Cytostatic Inhibition +8

Macrolides with gastrointestinal motor stimulating activity

Satoshi Ōmura, Kazuo Tsuzuki, Toshiaki Sunazuka, +4

Journal of Medicinal Chemistry

Zen ItohciteGastrointestinal PharmacologyImmunologyGastroenterologyAltmetric Attention Score +15

TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons

Koki Kato, Hitomi Hayako, Yuji Ishihara, +3

Neuroscience Letters

Molecular PhysiologyAcetylcholinesterase InhibitorBiochemistryNeurophysiologyMedicine +5

Motilides, macrolides with gastrointestinal motor stimulating activity. I. O-substituted and tertiary N-substituted derivatives of 8,9-anhydroerythromycin A 6,9-hemiacetal.

Kazuo Tsuzuki, Toshiaki Sunazuka, Shogo Marui, +4

Chemical and Pharmaceutical Bulletin

Tertiary N-substituted DerivativesMedicinal ChemistryBiochemistryAntibioticsGms Activity +12

Chemical Modification of Fumagillin. I. 6-O-Acyl, 6-O-Sulfonyl, 6-O-Alkyl, and 6-O-(N-Substituted-carbamoyl)fumagillols.

Shogo Marui, Fumio Itoh, Yoshio Kozai, +2

Chemical and Pharmaceutical Bulletin

Chemical ModificationOrganic ChemistryCompound 2Vascular Endothelial CellsOxidative Stress +16

Motilides, macrolides with gastrointestinal motor stimulating activity. II. Quaternary N-substituted derivatives of 8,9-anhydroerythromycin A 6,9-hemiacetal and 9,9-dihydroerythromycin A 6,9-epoxide.

Toshiaki Sunazuka, Kazuo Tsuzuki, Shogo Marui, +4

Chemical and Pharmaceutical Bulletin

Medicinal ChemistryBiochemistryGms ActivityMedicineNatural Sciences +10

EM-523, an erythromycin derivative, and motilin show similar contractile activity in isolated rabbit intestine.

Takashi Satoh, Nobuhiro Inatomi, Hiroshi Satoh, +3

Journal of Pharmacology and Experimental Therapeutics

Vagus-Dependent and Vagus-Independent Mechanisms of Action of the Erythromycin Derivative EM574 and Motilin in Dogs

Nobuhiro Inatomi, Fumihiko Sato, Shogo Marui, +2

The Japanese Journal of Pharmacology

GastroenterologyPharmacotherapyExperimental PharmacologyNeuromuscular BlockadeGastrointestinal Peptide Hormone +14

EM574, an erythromycin derivative, improves delayed gastric emptying of semi-solid meals in conscious dogs

Fumihiko Sako, Shogo Marui, Nobuhiro Inatomi, +2

European Journal of Pharmacology

Animal PhysiologyNutritionGastrointestinal PharmacologyMedicinePhysiology +7