Krista K. Bowman

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Till Maurer, Lindsay S. Garrenton, Angela Oh et al. · Proceedings of the National Academy of Sciences · 2012 · 630 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Oncogenic ERBB3 Mutations in Human Cancers

Bijay S. Jaiswal, Noelyn M. Kljavin, Eric Stawiski et al. · Cancer Cell · 2013 · 347 citations · Full text

Medicine, Genetics, Oncology +14

Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist

Shivani Ahuja, Susmith Mukund, Lunbin Deng et al. · Science · 2015 · 327 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Somatic Mutations in p85α Promote Tumorigenesis through Class IA PI3K Activation

Bijay S. Jaiswal, Vasantharajan Janakiraman, Noelyn M. Kljavin et al. · Cancer Cell · 2009 · 287 citations · Full text

Medicine, Molecular Biology, Oncology +14

Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

Xiaolei Ma, Elizabeth Helgason, Qui Phung et al. · Proceedings of the National Academy of Sciences · 2012 · 234 citations · Full text

Life Sciences, Immunology, Molecular Biology +16