José A López-Domínguez

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

Megan N. Roberts, Marita A. Wallace, Alexey Tomilov et al. · Cell Metabolism · 2017 · 506 citations · Full text

Lifespan Extension, Nutrition, Aging +8

Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

Anthony J. Covarrubias, Abhijit Kale, Rosalba Perrone et al. · Nature Metabolism · 2020 · 380 citations · Full text

Inflammation, Cd38+ Macrophages, Aging +11

Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis

Christopher D. Wiley, Rishi Sharma, Sonnet S. Davis et al. · Cell Metabolism · 2021 · 151 citations · Full text

Lifespan Extension, Biosynthesis, Biochemistry +9

SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells

Christopher D. Wiley, Su Liu, Chandani Limbad et al. · Cell Reports · 2019 · 129 citations · Full text

Immunology, Blood Cell, Cell Death +21

Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Christopher D. Wiley, Nicholas Schaum, Fatouma Alimirah et al. · Scientific Reports · 2018 · 116 citations · Full text