Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota

Guolin Li, Cen Xie, Siyu Lu, +12

Cell Metabolism

ObesityNutritionMetabolic SyndromeDecreases ObesityDysbiosis +10

Hepatic Niemann-Pick C1–like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

Ryan E. Temel, Weiqing Tang, Yinyan Ma, +6

Journal of Clinical Investigation

Plasma CholesterolCholangiopathiesCholangiocyte BiologyCellular PhysiologyMolecular Pharmacology +18

Lipolysis in Brown Adipocytes Is Not Essential for Cold-Induced Thermogenesis in Mice

Hyunsu Shin, Yinyan Ma, Tatyana Chanturiya, +9

Cell Metabolism

Energy MetabolismBiochemistryPhysiologyMetabolic SignalingBrown Adipocytes +9

Cholesterol-regulated Translocation of NPC1L1 to the Cell Surface Facilitates Free Cholesterol Uptake

Liqing Yu, Shantaram Bharadwaj, J. Mark Brown, +7

Journal of Biological Chemistry

Lipid MovementCellular PhysiologyCellular Cholesterol UptakeCholesterol UptakeEndocytic Pathway +15

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance

J. Mark Brown, Jenna L. Betters, Caleb C. Lord, +16

Journal of Lipid Research

Loss of Abhd5 Promotes Colorectal Tumor Development and Progression by Inducing Aerobic Glycolysis and Epithelial-Mesenchymal Transition

Juanjuan Ou, Hongming Miao, Yinyan Ma, +9

Cell Reports

Macrophage CGI-58 Deficiency Activates ROS-Inflammasome Pathway to Promote Insulin Resistance in Mice

Hongming Miao, Juanjuan Ou, Yinyan Ma, +15

Cell Reports

Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice

Feng Guo, Yinyan Ma, Anil K.G. Kadegowda, +10

Journal of Lipid Research

GeneticsPathologyFatty Liver DiseaseCirrhosisInflammation +19

Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis

Lin Jia, Yinyan Ma, Shunxing Rong, +6

Journal of Lipid Research

Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8

Weiqing Tang, Yinyan Ma, Lin Jia, +3

Journal of Lipid Research