The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C

Caleb C. Lord, Steven C. Wyler, Rong Wan, +6

Journal of Clinical Investigation

Psychotropic MedicationPsychopharmacologyNeuropsychiatryGlucose ToleranceSocial Sciences +19

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance

J. Mark Brown, Jenna L. Betters, Caleb C. Lord, +16

Journal of Lipid Research

The Serine Hydrolase ABHD6 Is a Critical Regulator of the Metabolic Syndrome

Gwynneth Thomas, Jenna L. Betters, Caleb C. Lord, +23

Cell Reports

POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels

Alexandre Caron, Heather M. Dungan Lemko, Carlos M. Castorena, +8

eLife

Biliary Sterol Secretion Is Not Required for Macrophage Reverse Cholesterol Transport

Ryan E. Temel, Janet K. Sawyer, Liqing Yu, +8

Cell Metabolism

OxysterolBiliary TractMedicinePhysiologyPathology +6

Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity

Renate Schreiber, Peter Hofer, Ulrike Taschler, +11

Proceedings of the National Academy of Sciences

Combined Therapy of Dietary Fish Oil and Stearoyl-CoA Desaturase 1 Inhibition Prevents the Metabolic Syndrome and Atherosclerosis

J. Mark Brown, Soonkyu Chung, Janet K. Sawyer, +15

Arteriosclerosis Thrombosis and Vascular Biology

Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease

Lin Jia, Xiuli Chang, Shuwen Qian, +10

Molecular Metabolism

CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action

Caleb C. Lord, Jenna L. Betters, Pavlina T. Ivanova, +15

Diabetes

Chronic Inflammatory DiseasesImmunologyInsulin SignalingInflammationMetabolic Syndrome +19

Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation

Caleb C. Lord, Daniel Ferguson, Gwynneth Thomas, +19

Cell Reports