Sachin Mahale

Design, synthesis and biological evaluation of new tryptamine and tetrahydro-β-carboline-based selective inhibitors of CDK4

Paul R. Jenkins, Daniel P. G. Emmerson, Marcos D. García et al. · Bioorganic & Medicinal Chemistry · 2008 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1

Carine Aubry, A. James Wilson, Daniel P. G. Emmerson et al. · Bioorganic & Medicinal Chemistry · 2009 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Design, synthesis and biological activity of new CDK4-specific inhibitors, based on fascaplysin

Carine Aubry, A. James Wilson, Paul R. Jenkins et al. · Organic & Biomolecular Chemistry · 2006 · 43 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Antitumour potential of BPT: a dual inhibitor of cdk4 and tubulin polymerization

Sachin Mahale, Sandip B. Bharate, Sudhakar Manda et al. · Cell Death and Disease · 2015 · 42 citations · Full text

Medicine, Oncology, Pharmacology +13

The design and synthesis of novel 3-[2-indol-1-yl-ethyl]-1H-indole derivatives as selective inhibitors of CDK4

Carine Aubry, Asma Patel, Sachin Mahale et al. · Tetrahedron Letters · 2005 · 42 citations

Pharmacy, Chemistry, Medicinal Chemistry +9