Carine Aubry

Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1

Carine Aubry, A. James Wilson, Daniel P. G. Emmerson et al. · Bioorganic & Medicinal Chemistry · 2009 · 45 citations · Full text

Medicine, Rational Drug Design, Fascaplysin-inspired Diindolyls +3

Design, synthesis and biological activity of new CDK4-specific inhibitors, based on fascaplysin

Carine Aubry, A. James Wilson, Paul R. Jenkins et al. · Organic & Biomolecular Chemistry · 2006 · 42 citations

The design and synthesis of novel 3-[2-indol-1-yl-ethyl]-1H-indole derivatives as selective inhibitors of CDK4

Carine Aubry, Asma Patel, Sachin Mahale et al. · Tetrahedron Letters · 2005 · 42 citations

Medicinal Chemistry, Natural Sciences, Drug Discovery +8

New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity

Carine Aubry, Paul R. Jenkins, Sachin Mahale et al. · Chemical Communications · 2004 · 35 citations

Biological Activity, Combinatorial Chemistry, Biochemistry +12

CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylation

Sachin Mahale, Carine Aubry, A. James Wilson et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 32 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +11