Heidi Jonckheere

Formatted anti–tumor necrosis factor α VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen‐induced arthritis

Ken Coppieters, Torsten Dreier, Karen Silence et al. · Arthritis & Rheumatism · 2006 · 301 citations

Medicine, Immunology, Molecular Biology +17

Resistance of HIV-1 reverse transcriptase against [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5“-(4”-amino-1“,2”- oxathiole-2“,2”-dioxide)] (TSAO) derivatives is determined by the mutation Glu138–>Lys on the p51 subunit.

Heidi Jonckheere, Jean‐Marc Taymans, Jan Balzarini et al. · Journal of Biological Chemistry · 1994 · 90 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

1,1,3-Trioxo-2 <i>H</i> ,4 <i>H</i> -Thieno[3,4- <i>e</i> ][1,2,4]Thiadiazine (TTD) Derivatives: a New Class of Nonnucleoside Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Inhibitors with Anti-HIV-1 Activity

Myriam Witvrouw, María Esther Arranz, Christophe Pannecouque et al. · Antimicrobial Agents and Chemotherapy · 1998 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Fidelity analysis of HIV‐1 reverse transcriptase mutants with an altered amino‐acid sequence at residues Leu74, Glu89, Tyr115, Tyr183 and Met184

Heidi Jonckheere, Erik De Clercq, Jozef Anné · European Journal of Biochemistry · 2000 · 41 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Mutational Analysis of Tyr-318 within the Non-nucleoside Reverse Transcriptase Inhibitor Binding Pocket of Human Immunodeficiency Virus Type I Reverse Transcriptase

Heidi Pelemans, Robert Esnouf, Heidi Jonckheere et al. · Journal of Biological Chemistry · 1998 · 31 citations · Full text

Life Sciences, Biology, Molecular Biology +15