Hydralazine may induce autoimmunity by inhibiting extracellular signal–regulated kinase pathway signaling

Chun Deng, Qianjin Lu, Zhiyong Zhang, +3

Arthritis & Rheumatism

DNA Methylation and Chromatin Structure Regulate T Cell Perforin Gene Expression

Qianjin Lu, Ailing Wu, Donna Ray, +5

The Journal of Immunology

Age-dependent DNA methylation changes in the ITGAL (CD11a) promoter

Zhiyong Zhang, Chun Deng, Qianjin Lu, +1

Mechanisms of Ageing and Development

BiologyChromatinTranscriptional RegulationNatural SciencesGenetics +7

Identification of Compounds with Nanomolar Binding Affinity for Checkpoint Kinase-1 Using Knowledge-Based Virtual Screening

Paul D. Lyne, Peter W. Kenny, David A. Cosgrove, +4

Journal of Medicinal Chemistry

Drug TargetHit IdentificationMolecular BiologyTumor BiologyMedicinal Chemistry +18

Role of the ras-MAPK Signaling Pathway in the DNA Methyltransferase Response to DNA Hypomethylation

Chun Deng, Jun Yang, Jeannine M. Scott, +2

Biological Chemistry

Relationship between Matrix Metalloproteinase 2 and Lung Cancer Progression

Chunbao Guo, Shan Wang, Chun Deng, +3

Molecular Diagnosis & Therapy

Tumor BiologyLung Cancer ProgressionPathologyBronchial NeoplasmLung Cancer +4

Glutamate Ionotropic Receptor Kainate Type Subunit 3 (GRIK3) promotes epithelial‐mesenchymal transition in breast cancer cells by regulating SPDEF/CDH1 signaling

Bin Xiao, Zhenzhan Kuang, Weiyun Zhang, +11

Molecular Carcinogenesis

Potential biomarkers involving IKK/RelA signal in early stage non‐small cell lung cancer

Xianqing Jin, Ziming Wang, Lin Qiu, +7

Cancer Science

Effect of mitogenic stimulation and DNA methylation on human T cell DNA methyltransferase expression and activity

Jun Yang, Chun Deng, Nahid Hemati, +2

The Journal of Immunology

Unexpected Effects of a Heterozygous Dnmt1 Null Mutation on Age-Dependent DNA Hypomethylation and Autoimmunity

Raymond Yung, David Ray, Julie K. Eisenbraun, +6

The Journals of Gerontology Series A

Unexpected EffectsEpigenetic ChangeGeneticsDna MethylationImmunology +17