David A. Cosgrove

Matched Molecular Pairs as a Guide in the Optimization of Pharmaceutical Properties; a Study of Aqueous Solubility, Plasma Protein Binding and Oral Exposure

Andrew G. Leach, Huw Jones, David A. Cosgrove et al. · Journal of Medicinal Chemistry · 2006 · 280 citations

Pharmaceutical Science, Chemical Analysis, Pharmaceutical Properties +21

Identification of Compounds with Nanomolar Binding Affinity for Checkpoint Kinase-1 Using Knowledge-Based Virtual Screening

Paul D. Lyne, Peter W. Kenny, David A. Cosgrove et al. · Journal of Medicinal Chemistry · 2004 · 111 citations · Full text

Drug Target, Hit Identification, Molecular Biology +20

Scaffold Hopping Using Clique Detection Applied to Reduced Graphs

Edward J. Barker, David Buttar, David A. Cosgrove et al. · Journal of Chemical Information and Modeling · 2006 · 86 citations

Design of compound libraries for fragment screening

Niklas Blomberg, David A. Cosgrove, Peter W. Kenny et al. · Journal of Computer-Aided Molecular Design · 2009 · 79 citations

Targeted Library, Mass Spectrometry, Compound Libraries +8

Lead Hopping Using SVM and 3D Pharmacophore Fingerprints

Jamal Saeh, Paul D. Lyne, Bryan K. Takasaki et al. · Journal of Chemical Information and Modeling · 2005 · 56 citations