Ayako Moritomo

Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor

Hisao Hamaguchi, Y. Amano, Ayako Moritomo et al. · Bioorganic & Medicinal Chemistry · 2018 · 80 citations · Full text

Medicinal Chemistry, Structural Characterization, Drug Target +11

Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors

S. Nagashima, Takeshi Hondo, Hiroshi Nagata et al. · Bioorganic & Medicinal Chemistry · 2009 · 47 citations

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +9

Novel 1H-imidazol-2-amine derivatives as potent and orally active vascular adhesion protein-1 (VAP-1) inhibitors for diabetic macular edema treatment

Takayuki Inoue, Masataka Morita, Takashi Tojo et al. · Bioorganic & Medicinal Chemistry · 2013 · 31 citations · Full text

Pharmaceutical Science, Ocular Disease, Pharmacotherapy +21

Small-World Phenomena in Chemical Library Networks: Application to Fragment-Based Drug Discovery

Naoki Tanaka, Kazuki Ohno, Tatsuya Niimi et al. · Journal of Chemical Information and Modeling · 2009 · 29 citations

Engineering, Hit Identification, Molecular Biology +20

Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema

Takayuki Inoue, Masataka Morita, Takashi Tojo et al. · Bioorganic & Medicinal Chemistry · 2012 · 25 citations · Full text

Ophthalmology, Medicine, Vascular Pharmacology +8