Richard B. Presland

Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris

Frances J.D. Smith, Alan D. Irvine, Ana Terron-Kwiatkowski et al. · Nature Genetics · 2006 · 1K citations

Life Sciences, Genetics, Molecular Genetics +9

A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming

Padraic G. Fallon, Takashi Sasaki, Aileen Sandilands et al. · Nature Genetics · 2009 · 471 citations · Full text

Life Sciences, Genetics, Molecular Genetics +7

Caspase-14 protects against epidermal UVB photodamage and water loss

Geertrui Denecker, Esther Hoste, Barbara Gilbert et al. · Nature Cell Biology · 2007 · 294 citations

Life Sciences, Cell Biology, Dermatology +16

Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure and Function

Robert Gruber, Peter M. Elias, Debra Crumrine et al. · American Journal Of Pathology · 2011 · 239 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Caspase-14 Is Required for Filaggrin Degradation to Natural Moisturizing Factors in the Skin

Esther Hoste, P. M. J. H. Kemperman, Michaël Devos et al. · Journal of Investigative Dermatology · 2011 · 215 citations · Full text

Medicine, Cell Biology, Dermatology +14