Mild and Efficient DBU-Catalyzed Amidation of Cyanoacetates

Kristin E. Price, Claude Larrivee‐Aboussafy, Brett M. Lillie, +5

Organic Letters

Cyanoacetic AcidPractical ProtocolBioorganic ChemistryEfficient Dbu-catalyzed AmidationEngineering +10

Machine learning directed multi-objective optimization of mixed variable chemical systems

Oliver J. Kershaw, Adam D. Clayton, Jamie A. Manson, +8

Chemical Engineering Journal

EngineeringMachine LearningComputational ChemistryChemistryChemical Engineering +14

Commercial Route Research and Development for SGLT2 Inhibitor Candidate Ertugliflozin

Paul Bowles, Steven J. Brenek, Stéphane Caron, +21

Organic Process Research & Development

Combinatorial ChemistryBioorganic ChemistryOrganic ChemistryPharmacotherapyMethylpiperazine Amide +17

Development of a Scalable Process for CI-1034, an Endothelin Antagonist

Thomas E. Jacks, Daniel T. Belmont, Christopher A. Briggs, +12

Organic Process Research & Development

Organic ChemistryPharmacotherapyChemistryHeterocycle ChemistryExperimental Pharmacology +16

API Quality by Design Example from the Torcetrapib Manufacturing Process

David J. am Ende, Karen S. Bronk, Jason Mustakis, +4

Journal of Pharmaceutical Innovation

Industrial DesignQuality AssuranceEngineeringSoftware QualityApi Quality +9

Applications of Quantum Chemistry in Pharmaceutical Process Development: Current State and Opportunities

Yu‐hong Lam, Yuriy A. Abramov, Ravi S. Ananthula, +8

Organic Process Research & Development

EngineeringProcess DevelopmentOrganic ChemistryComputational ChemistryChemistry +24

Probing the chemical ‘reactome’ with high-throughput experimentation data

Emma King‐Smith, Simon Berritt, Louise Bernier, +8

Nature Chemistry

EngineeringChemical AnalysisMolecular BiologyOrganic ChemistryComputational Chemistry +14

Development of a Small-Scale Automated Solubility Measurement Apparatus

Yongjin Yi, Dimitri Hatziavramidis, Allan S. Myerson, +3

Industrial & Engineering Chemistry Research

Pharmaceutical ScienceEngineeringMeasurementChemistryMineral Processing +20

Continuous Production of Anhydrous <i>tert</i>-Butyl Hydroperoxide in Nonane Using Membrane Pervaporation and Its Application in Flow Oxidation of a γ-Butyrolactam

Bryan Li, Steven M. Guinness, Steve Hoagland, +19

Organic Process Research & Development

Advanced Oxidation ProcessMedicinal ChemistryChemical EngineeringEngineeringPharmaceutical Chemistry +13

Kinetic Modeling of API Oxidation: (2) Imipramine Stress Testing

Haoyang Wu, Alon Grinberg Dana, Duminda S. Ranasinghe, +6

Molecular Pharmaceutics