PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage

Ekaterina Bobrovnikova-Marjon, Christina Grigoriadou, Dariusz Pytel, +5

Oncogene

Tumor BiologyCancer Cell ProliferationOxidative Dna DamageOncogenic AgentMedicine +9

miR-211 Is a Prosurvival MicroRNA that Regulates chop Expression in a PERK-Dependent Manner

Nilesh Chitnis, Dariusz Pytel, Ekaterina Bobrovnikova-Marjon, +9

Molecular Cell

Prosurvival MicrornaTranscriptional RegulationEngineeringChop ExpressionMedicine +10

PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation

Ekaterina Bobrovnikova-Marjon, Dariusz Pytel, Matthew J. Riese, +5

Molecular and Cellular Biology

Mediate Akt ActivationCell DeathEr StressCellular PhysiologyInsulin Signaling +19

Antibacterial, Anti‐Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of <i>Leonurus sibiricus</i> L. and Their Chemical Composition

Przemysław Sitarek, Patrícia Rijo, Catarina García, +8

Oxidative Medicine and Cellular Longevity

The ζ Isoform of Diacylglycerol Kinase Plays a Predominant Role in Regulatory T Cell Development and TCR-Mediated Ras Signaling

Rohan P. Joshi, Amanda M. Schmidt, Jayajit Das, +7

Science Signaling

T-regulatory CellImmunologyImmune RegulationT CellsTcr-stimulated Ras Activation +15

BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability

Artur Słupianek, Tomasz Popławski, Stanisław K. Jóźwiakowski, +6

Cancer Research

Werner SyndromeMixed-phenotype Acute LeukemiaGeneticsLesions Bcr/ablMolecular Biology +19

Induction of apoptosis by in vitro and in vivo plant extracts derived from Menyanthes trifoliata L. in human cancer cells

Tomasz Kowalczyk, Przemysław Sitarek, Ewa Skała, +6

Cytotechnology

Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mo mathvariant="bold">β</mml:mo></mml:mrow></mml:math>as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients

Łukasz Markiewicz, Dariusz Pytel, Bartosz Mucha, +2

BioMed Research International

PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma

Dariusz Pytel, Yan Gao, Katarzyna Mackiewicz, +12

PLoS Genetics

Cancer ResearchCell RegulationHuman MelanomaMedicineHaploinsufficient Tumor Suppressor +13

BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability

Rafal Falinski, Paweł Znojek, Sylwia Flis, +5

Leukemia

Reductive StressGenome InstabilityOxidative Dna DamageGeneticsGenomic Mechanism +4