Xurde M. Caravia

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism

Clea Bárcena, Pedro M. Quirós, Sylvère Durand et al. · Cell Reports · 2018 · 186 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +17

Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease

Simon Lebek, Francesco Chemello, Xurde M. Caravia et al. · Science · 2023 · 120 citations · Full text

Life Sciences, Cardiology, Genetics +16

The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function

Xurde M. Caravia, Víctor Fanjul, Eduardo Oliver et al. · PLoS Biology · 2018 · 70 citations · Full text

Life Sciences, Cardiology, Molecular Biology +17

CRISPR-Cas9 base editing of pathogenic CaMKIIδ improves cardiac function in a humanized mouse model

Simon Lebek, Xurde M. Caravia, Leon G. Straub et al. · Journal of Clinical Investigation · 2023 · 39 citations · Full text

Life Sciences, Biotechnology, Cardiology +16

Elimination of CaMKIIδ Autophosphorylation by CRISPR-Cas9 Base Editing Improves Survival and Cardiac Function in Heart Failure in Mice

Simon Lebek, Xurde M. Caravia, Francesco Chemello et al. · Circulation · 2023 · 33 citations · Full text

Life Sciences, Genetics, Molecular Biology +17