Katheryne Z. Edson

Cytochrome P450-Dependent Catabolism of Vitamin K: ω-Hydroxylation Catalyzed by Human CYP4F2 and CYP4F11

Katheryne Z. Edson, Bhagwat Prasad, Jashvant D. Unadkat et al. · Biochemistry · 2013 · 81 citations

Medicine, Biochemistry, Pharmacology +14

Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers

Marc Payton, Brian Belmontes, Kelly Hanestad et al. · Nature Cancer · 2023 · 68 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Nonclinical Pharmacokinetics, Disposition, and Drug-Drug Interaction Potential of a Novel d-Amino Acid Peptide Agonist of the Calcium-Sensing Receptor AMG 416 (Etelcalcetide)

Raju Subramanian, Xiaochun Zhu, Savannah J. Kerr et al. · Drug Metabolism and Disposition · 2016 · 39 citations

Medicine, Pharmacokinetics, Pharmacology +17

Optimized human CYP4B1 in combination with the alkylator prodrug 4-ipomeanol serves as a novel suicide gene system for adoptive T-cell therapies

Katharina Roellecke, Elizabeth L. Virts, Ralf Einholz et al. · Gene Therapy · 2016 · 34 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe

Nuria Tamayo, Matthew P. Bourbeau, Jennifer R. Allen et al. · Journal of Medicinal Chemistry · 2022 · 27 citations · Full text

Life Sciences, Molecular Biology, Oncology +16