Ruthger van Roey

Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition

Annemarie Schwab, Zhigang Rao, Jie Zhang et al. · Nature Cell Biology · 2024 · 119 citations · Full text

A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease

Luuk de Haan, Johnny Suijker, Ruthger van Roey et al. · International Journal of Molecular Sciences · 2021 · 76 citations · Full text

Engineering, Immunology, Biological Microenvironments +29

The <scp>EMT</scp> transcription factor <scp>ZEB1</scp> blocks osteoblastic differentiation in bone development and osteosarcoma

Manuel Ruh, Marc P. Stemmler, Isabell Frisch et al. · The Journal of Pathology · 2021 · 31 citations · Full text

Sclerostin, Pathology, Osteosarcoma Cells +23

The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response

Harald Schuhwerk, Julia Kleemann, Pooja Gupta et al. · Cell Reports · 2022 · 18 citations · Full text

ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer

Constantin Menche, Harald Schuhwerk, Isabell Armstark et al. · EMBO Reports · 2024 · 15 citations · Full text