Val S. Goodfellow

Mixed lineage kinase 3 mediates release of C‐X‐C motif ligand 10–bearing chemotactic extracellular vesicles from lipotoxic hepatocytes

Samar H. Ibrahim, Petra Hirsova, Kyoko Tomita et al. · Hepatology · 2015 · 231 citations

Life Sciences, Cell Biology, Immunology +17

Discovery, Synthesis, and Characterization of an Orally Bioavailable, Brain Penetrant Inhibitor of Mixed Lineage Kinase 3

Val S. Goodfellow, Colin J. Loweth, Torsten Wiemann et al. · Journal of Medicinal Chemistry · 2013 · 90 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

The New Small-Molecule Mixed-Lineage Kinase 3 Inhibitor URMC-099 Is Neuroprotective and Anti-Inflammatory in Models of Human Immunodeficiency Virus-Associated Neurocognitive Disorders

Daniel F. Marker, Marie‐Ève Tremblay, Jenna M. Puccini et al. · Journal of Neuroscience · 2013 · 67 citations · Full text

Medicine, Neurology, Neuroscience +15

Potent imidazole and triazole CB 1 receptor antagonists related to SR141716

Brian Dyck, Val S. Goodfellow, Teresa A. Phillips et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 65 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

A Thienopyridazinone-Based Melanin-Concentrating Hormone Receptor 1 Antagonist with Potent in Vivo Anorectic Properties

Brian Dyck, Stacy Markison, Liren Zhao et al. · Journal of Medicinal Chemistry · 2006 · 43 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +8