Concepedia

Motoo Nagane

MN

Statistics

Publications

91

Citations

7.9K

H-Index

45

Active since

1992

Affiliations

Kyorin University(Current)

Saitama Medical University

The University of Tokyo

Tohoku University

Yokohama City University

Motoo Nagane is an author at Kyorin University specializing in oncology, medicine, and molecular oncology.

Publications per year

1992–2024

91

Publications

91

The Enhanced Tumorigenic Activity of a Mutant Epidermal Growth Factor Receptor Common in Human Cancers Is Mediated by Threshold Levels of Constitutive Tyrosine Phosphorylation and Unattenuated Signaling

Hongyi Huang, Motoo Nagane, Candice K. Klingbeil et al. · Journal of Biological Chemistry · 1997 · 591 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis.

Motoo Nagane, Frank Coufal, Hong Lin et al. · PubMed · 1996 · 413 citations

Medicine, Cancer Biology, Oncology +14

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo.

Motoo Nagane, Guohua Pan, J J Weddle et al. · PubMed · 2000 · 392 citations

Life Sciences, Oncology, Pharmacology +17

Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas

Ana Guerreiro Stücklin, Scott Ryall, Kohei Fukuoka et al. · Nature Communications · 2019 · 373 citations · Full text

Medicine, Cancer Biology, Oncology +15

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-X <sub>L</sub> and caspase-3-like proteases

Motoo Nagane, Alexander Levitzki, Aviv Gazit et al. · Proceedings of the National Academy of Sciences · 1998 · 354 citations · Full text

Medicine, Oncology, Pharmacology +17

1–5 of 91