Hiroyuki Koshio

Antithrombotic effects of YM‐60828, a newly synthesized factor Xa inhibitor, in rat thrombosis models and its effects on bleeding time

Kazuo Sato, Tomihisa Kawasaki, Nami Hisamichi et al. · British Journal of Pharmacology · 1998 · 55 citations · Full text

YM-60828, a novel factor Xa inhibitor: Separation of its antithrombotic effects from its prolongation of bleeding time

Kazuo Sato, Tomihisa Kawasaki, Yuta Taniuchi et al. · European Journal of Pharmacology · 1997 · 51 citations

Thrombopoiesis, Thrombosis, Bleeding Time +11

Comparative Studies of an Orally-active Factor Xa Inhibitor, YM-60828, with other Antithrombotic Agents in a Rat Model of Arterial Thrombosis

Kazuo Sato, Yumiko Sakai, Fukushi Hirayama et al. · Thrombosis and Haemostasis · 1998 · 41 citations

Pharmacotherapy, Rat Model, Thrombosis +21

The Discovery of YM-60828: A Potent, Selective and Orally-Bioavailable Factor Xa Inhibitor

Fukushi Hirayama, Hiroyuki Koshio, Naoko Katayama et al. · Bioorganic & Medicinal Chemistry · 2002 · 36 citations

Biochemistry, Medicine, Mechanism Of Action +5

Nonpeptide Arginine Vasopressin Antagonists for Both V1A and V2 Receptors: Synthesis and Pharmacological Properties of 2-Phenyl-4'-(2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1-carbonyl)benzanilide Derivatives.

Akira Matsuhisa, Hiroyuki Koshio, Kenichiro Sakamoto et al. · Chemical and Pharmaceutical Bulletin · 1998 · 36 citations · Full text

V2 Receptors, Medicinal Chemistry, Pharmaceutical Science +15