Carolyn Nouhan

Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors:  The Profound Effect of Polarity on Antiviral Activity

Susan E. Hagen, J. V. N. Vara Prasad, F Boyer et al. · Journal of Medicinal Chemistry · 1997 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

4-Hydroxy-5,6-dihydropyrones as Inhibitors of HIV Protease:  The Effect of Heterocyclic Substituents at C-6 on Antiviral Potency and Pharmacokinetic Parameters

Susan E. Hagen, John M. Domagala, Christopher Gajda et al. · Journal of Medicinal Chemistry · 2001 · 59 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities:  Potent Nonpeptidic Inhibitors of HIV Protease

F Boyer, J. V. N. Vara Prasad, John M. Domagala et al. · Journal of Medicinal Chemistry · 2000 · 50 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +16

4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV Protease

Bradley D. Tait, Susan E. Hagen, John M. Domagala et al. · Journal of Medicinal Chemistry · 1997 · 48 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery and optimization of nonpeptide HIV-1 protease inhibitors

Peter J. Tummino, J. V. N. Vara Prasad, Donna Ferguson et al. · Bioorganic & Medicinal Chemistry · 1996 · 29 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +12