Michael J. Bogusky

Discovery of the Dual Orexin Receptor Antagonist [(7<i>R</i>)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2<i>H</i>-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia

Christopher D. Cox, Michael J. Breslin, David B. Whitman et al. · Journal of Medicinal Chemistry · 2010 · 370 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12

Cyclopsychotride A, a Biologically Active, 31-Residue Cyclic Peptide Isolated from Psychotria longipes

Keith M. Witherup, Michael J. Bogusky, Paul Anderson et al. · Journal of Natural Products · 1994 · 259 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Two Tarantula Peptides Inhibit Activation of Multiple Sodium Channels

Richard E. Middleton, Vivien A. Warren, Richard L. Kraus et al. · Biochemistry · 2002 · 233 citations

Medicine, Neuroscience, Pharmacology +17

Discovery of [(2<i>R</i>,5<i>R</i>)‐5‐{[(5‐Fluoropyridin‐2‐yl)oxy]methyl}‐2‐methylpiperidin‐1‐yl][5‐methyl‐2‐(pyrimidin‐2‐yl)phenyl]methanone (MK‐6096): A Dual Orexin Receptor Antagonist with Potent Sleep‐Promoting Properties

Paul J. Coleman, John D. Schreier, Christopher D. Cox et al. · ChemMedChem · 2012 · 124 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Enhancement of α-Helicity in the HIV-1 Inhibitory Peptide DP178 Leads to an Increased Affinity for Human Monoclonal Antibody 2F5 but Does Not Elicit Neutralizing Responses in Vitro

Joseph G. Joyce, William M. Hurni, Michael J. Bogusky et al. · Journal of Biological Chemistry · 2002 · 118 citations · Full text

Life Sciences, Immunology, Molecular Biology +17