Ajit K. Parhi

Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines

Ajit K. Parhi, Yong‐Zheng Zhang, Kurt W. Saionz et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 157 citations · Full text

Bioorganic Chemistry, Antibiotics, Medicine +8

TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced <i>In Vivo</i> Efficacy against Methicillin-Resistant Staphylococcus aureus

Malvika Kaul, Lilly Mark, Yongzheng Zhang et al. · Antimicrobial Agents and Chemotherapy · 2015 · 108 citations · Full text

Antimicrobial Chemotherapy, Pharmaceutical Chemistry, Drug Resistance +22

Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors

Joseph D. Bauman, Disha Patel, Steven F. Baker et al. · ACS Chemical Biology · 2013 · 84 citations · Full text

Structural Bioinformatics, Biomolecular Structure Prediction, Molecular Biology +18

Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in <i>Staphylococcus aureus</i> FtsZ

Junso Fujita, Yoko Maeda, Eiichi Mizohata et al. · ACS Chemical Biology · 2017 · 67 citations · Full text

Crystal Structure, Structural Bioinformatics, Biomolecular Structure Prediction +22

3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents

Cody Kelley, Yongzheng Zhang, Ajit K. Parhi et al. · Bioorganic & Medicinal Chemistry · 2012 · 66 citations · Full text

Medicinal Chemistry, Medicine, Antibacterial Agent +4