Patients With Antithyroid Antibodies Are Prone To Develop Destructive Thyroiditis by Nivolumab: A Prospective Study

Tomoko Kobayashi, Shintaro Iwama, Yoshinori Yasuda, +20

Journal of the Endocrine Society

Flash glucose monitoring helps achieve better glycemic control than conventional self-monitoring of blood glucose in non-insulin-treated type 2 diabetes: a randomized controlled trial

Eri Wada, Takeshi Onoue, Tomoko Kobayashi, +18

BMJ Open Diabetes Research & Care

Pituitary dysfunction induced by immune checkpoint inhibitors is associated with better overall survival in both malignant melanoma and non-small cell lung carcinoma: a prospective study

Tomoko Kobayashi, Shintaro Iwama, Yoshinori Yasuda, +23

Journal for ImmunoTherapy of Cancer

Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells

Takatoshi Kasai, Hidetaka Suga, Mayu Sakakibara, +19

Cell Reports

Independent Pituitary InductionHypothalamic CircuitsEmbryologyPituitary GlandNeuroendocrine Mechanism +20

CD4 ⁺ T cells are essential for the development of destructive thyroiditis induced by anti–PD-1 antibody in thyroglobulin-immunized mice

Yoshinori Yasuda, Shintaro Iwama, Daisuke Sugiyama, +19

Science Translational Medicine

Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study

Norio Okada, Shintaro Iwama, Takayuki Okuji, +29

British Journal of Cancer

Anti-pituitary antibodies and susceptible human leukocyte antigen alleles as predictive biomarkers for pituitary dysfunction induced by immune checkpoint inhibitors

Tomoko Kobayashi, Shintaro Iwama, Daisuke Sugiyama, +13

Journal for ImmunoTherapy of Cancer

Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia

Taku Tsunekawa, Ryoichi Banno, Akira Mizoguchi, +10

EBioMedicine

Increased Risk of Thyroid Dysfunction by PD-1 and CTLA-4 Blockade in Patients Without Thyroid Autoantibodies at Baseline

Shintaro Iwama, Tomoko Kobayashi, Yoshinori Yasuda, +38

The Journal of Clinical Endocrinology & Metabolism

Endoplasmic reticulum chaperone BiP/GRP78 knockdown leads to autophagy and cell death of arginine vasopressin neurons in mice

Yohei Kawaguchi, Daisuke Hagiwara, Takashi Miyata, +12

Scientific Reports