Actively personalized vaccination trial for newly diagnosed glioblastoma

Norbert Hilf, Sabrina Kuttruff-Coqui, Katrin Frenzel, +61

Nature

VaccinationNeuro-oncologyVaccination TrialVaccine TrialTherapeutic Vaccine +4

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

Steffen Walter, Toni Weinschenk, Arnulf Stenzl, +35

Nature Medicine

VaccinationCancer ImmunosurveillanceMultipeptide Immune ResponseMedicineCancer Vaccine Ima901 +10

The Endoplasmic Reticulum-resident Heat Shock Protein Gp96 Activates Dendritic Cells via the Toll-like Receptor 2/4 Pathway

R. Martin Vabulas, Sibylla Braedel, Norbert Hilf, +8

Journal of Biological Chemistry

The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor

Harpreet Singh‐Jasuja, Hans Ulrich Scherer, Norbert Hilf, +4

European Journal of Immunology

Cross-Presentation of Glycoprotein 96–Associated Antigens on Major Histocompatibility Complex Class I Molecules Requires Receptor-Mediated Endocytosis

Harpreet Singh‐Jasuja, René E. M. Toes, Pieter Spee, +8

The Journal of Experimental Medicine

Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses

M. Hipp, Norbert Hilf, Steffen Walter, +6

Blood

Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy

Valérie Dutoit, Christel Herold‐Mende, Norbert Hilf, +17

Brain

A Cancer Research UK First Time in Human Phase I Trial of IMA950 (Novel Multipeptide Therapeutic Vaccine) in Patients with Newly Diagnosed Glioblastoma

R. Rampling, Sharon Peoples, Paul Mulholland, +16

Clinical Cancer Research

Human platelets express heat shock protein receptors and regulate dendritic cell maturation

Norbert Hilf, Harpreet Singh‐Jasuja, Petra Schwarzmaier, +3

Blood

The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor

Harpreet Singh-Jasuja, Hans Ulrich Scherer, Norbert Hilf, +4

European Journal of Immunology

Signal TransductionG Protein-coupled ReceptorCell InteractionImmunologyMedicine +4