Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States

Wei Sun, Jing Yang, Zhi Cheng, +14

Molecular Cell

MedicineMolecular BiologyGene EditingGenome EditingMicrobiology +5

Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2

Annoj Thavalingam, Zhi Cheng, Bianca Garcı́a, +13

Nature Communications

Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2

Xue Huang, Wei Sun, Zhi Cheng, +6

Nature Communications

Integrated omics analysis reveals the alteration of gut microbe–metabolites in obese adults

Rong Li, Xue Huang, Liang Xiao, +3

Briefings in Bioinformatics

ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression

Jianze Xu, Jianing Gao, Junyan Liu, +16

Cell Reports

SpermatogenesisGeneticsReproductive BiologyEpigeneticsFertilisation +20

Analyzing the synergistic adverse effects of BPA and its substitute, BHPF, on ulcerative colitis through comparative metabolomics

Feiying Yin, Xue Huang, Xiao Lin, +3

Chemosphere

GastroenterologyMetabolomic ProfilingSynergistic Adverse EffectsComparative MetabolomicsUlcerative Colitis +7

Integrated Analysis Reveals the Targets and Mechanisms in Immunosuppressive Effect of Mesalazine on Ulcerative Colitis

Rong Li, Xue Huang, Lu Yang, +4

Frontiers in Nutrition

Mechanism of Resveratrol on LPS/ATP-induced pyroptosis and inflammatory response in HT29 cells

Peizhuang Zhao, Jiajia Ning, Jun Huang, +1

Autoimmunity

Discovery of core genes in colorectal cancer by weighted gene co‑expression network analysis

Cun Liao, Xue Huang, Yizhen Gong, +1

Oncology Letters

Effects of Resveratrol on Tight Junction Proteins and the Notch1 Pathway in an HT-29 Cell Model of Inflammation Induced by Lipopolysaccharide

Yihua Luo, Xueyan Yu, Peizhuang Zhao, +2

Inflammation

InflammationReductive StressSignal TransductionBiochemistryTight Junction Proteins +10