Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

Young Chan Chae, Valentina Vaira, M. Cecilia Caino, +16

Cancer Cell

Mitochondrial FunctionMitochondrial Akt RegulationMedicineCell BiologyTumor Microenvironment +1

Comparison of Methods for Quantification of Global DNA Methylation in Human Cells and Tissues

Sofia Lisanti, Wan Adnan Wan Omar, Bartłomiej Tomaszewski, +5

PLoS ONE

Landscape of the mitochondrial Hsp90 metabolome in tumours

Young Chan Chae, Alessia Angelin, Sofia Lisanti, +13

Nature Communications

Mitochondrial FunctionMedicineMitochondrial Hsp90 MetabolomeCell BiologyCancer Research +1

Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s

Young Chan Chae, M. Cecilia Caino, Sofia Lisanti, +11

Cancer Cell

Reductive StressTumor BiologyMitophagyMitochondrial FunctionCell Death +9

Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy

Jagadish C. Ghosh, Markus D. Siegelin, Valentina Vaira, +14

JNCI Journal of the National Cancer Institute

Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks

Sofia Lisanti, Michele Tavecchio, Young Chan Chae, +5

Cell Reports

Karyopherin-α2 Protein Interacts with Chk2 and Contributes to Its Nuclear Import

Laura Zannini, Daniele Lecis, Sofia Lisanti, +4

Journal of Biological Chemistry

The Shelterin Protein TRF2 Inhibits Chk2 Activity at Telomeres in the Absence of DNA Damage

Giacomo Buscemi, Laura Zannini, Enrico Fontanella, +3

Current Biology

ChromatinGenome InstabilityProtein FunctionDna DamageNatural Sciences +5

Epigenetic mechanisms underlying arsenic-associated lung carcinogenesis

Simone G. van Breda, Sandra M.H. Claessen, Ken C. Lo, +8

Archives of Toxicology

ChromatinArsenic-associated Lung CarcinogenesisEpigenetic ChangeEpigenomicsMedicine +4

Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism

Michele Tavecchio, Sofia Lisanti, Michael J. Bennett, +2

Scientific Reports