Markus D. Siegelin

HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models

Trang Nguyen, Yiru Zhang, Enyuan Shang et al. · Journal of Clinical Investigation · 2020 · 198 citations · Full text

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

Jana Biermann, Johannes C. Melms, Amit Dipak Amin et al. · Cell · 2022 · 194 citations · Full text

Neuro-oncology, Melanoma, Treatment-naive Ecosystem +4

Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells

Jagadish C. Ghosh, Markus D. Siegelin, Takehiko Dohi et al. · Cancer Research · 2010 · 193 citations · Full text

Mitophagy, Tumor Maintenance, Apoptosis +16

Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Pavan S. Upadhyayula, Dominique Higgins, Angeliki Mela et al. · Nature Communications · 2023 · 162 citations · Full text

Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells

Markus D. Siegelin, Takehiko Dohi, Christopher M. Raskett et al. · Journal of Clinical Investigation · 2011 · 155 citations · Full text