Markus D. Siegelin

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

Jana Biermann, Johannes C. Melms, Amit Dipak Amin et al. · Cell · 2022 · 211 citations · Full text

Medicine, Neuroscience, Oncology +14

HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models

Trang Nguyen, Yiru Zhang, Enyuan Shang et al. · Journal of Clinical Investigation · 2020 · 207 citations · Full text

Medicine, Cancer Biology, Oncology +17

Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells

Jagadish C. Ghosh, Markus D. Siegelin, Takehiko Dohi et al. · Cancer Research · 2010 · 195 citations · Full text

Life Sciences, Molecular Biology, Oncology +13

Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Pavan S. Upadhyayula, Dominique Higgins, Angeliki Mela et al. · Nature Communications · 2023 · 185 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +17

Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells

Markus D. Siegelin, Takehiko Dohi, Christopher M. Raskett et al. · Journal of Clinical Investigation · 2011 · 158 citations · Full text

Life Sciences, Molecular Biology, Oncology +17